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REVEAL 2.0 Risk Calculator
Score
Select all variables that apply. A minimum of
7
variables are required to generate a score. Calculation accuracy increases with more selections.
WHO Group 1 Subgroup
Other
0
CTD-PAH
1
PoPH
3
Heritable
2
--
Demographics -
Male age > 60 years
No
0
Yes
2
--
eGFR<60mL/min/1.73m² or renal insufficiency
No
0
Yes
1
--
NYHA/WHO
Functional Class
I
-1
II
0
III
1
IV
2
--
Systolic BP (mm Hg)
SBP≥110
0
SBP<110
1
--
Heart Rate (BPM)
HR≤96
0
HR>96
1
--
All-Cause Hospitalizations ≤ 6 mo
No
0
Yes
1
--
6-Minute Walk Test (m)
≥440
-2
320 to 440
-1
<320 to 165
0
<165
1
--
BNP (pg/mL)
50
-2
50 to <200
0
200 to <800
1
≥800
2
--
or
NT-proBNP (pg/mL)
<300
-2
300 to <1100
0
≥1100
2
--
Pericardial Effusion on Echocardiogram
No
0
Yes
1
--
% predicted DL
CO
≤40
No
0
Yes
1
--
mRAP >20 mm Hg Within 1 Year
No
0
Yes
1
--
PVR < 5 Wood units on right heart catheterization
No
0
Yes
-1
--
--
+6
Risk score
Low risk
Intermediate risk
High risk
Risk score
0-6
7-8
≥9
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APAH=associated pulmonary arterial hypertension; BNP=B-type natriuretic peptide; BPM=beats per minute; CTD=connective tissue disease;DL
CO
=diffusing capacity of the lung for carbon monoxide; eGFR=estimated glomerular filtration rate; FPAH=familial pulmonary atrial hypertension; HR=heart rate; mRAP=mean right atrial pressure; NT-proBNP=N-terminal pro-B-type natriuretic peptide; NYHA=New York Heart Association; PAH=pulmonary arterial hypertension; PoPH=portopulmonary hypertension; PVR=pulmonary vascular resistance; REVEAL=Registry to EValuate Early And Long-term pulmonary arterial hypertension disease management; SBP=systolic blood pressure; WHO=World Health Organization
Reference: Benza RL, et al.
Chest.
2019;156(2):323-337.
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